Posts tagged ‘jacqui-murray’
THE SUPERIOR SPECIES: CONTINUED
NEW HAVEN, CONNETICUT
It was a wild night with a howling and frigid wind buffeting the windows of the senior faculty house on the Yale campus. Sheets of rain kept all the details of the world beyond the windows indefinite.
Four men, leaders in their fields, sat before a roaring fire, the flames reflecting off the dark wooden panels of the study walls. Each man held a brandy stiffer and appreciated the ambiance of the room and the moment. The men were in one of the faculty houses provided to senior members of Yale. The residence was that of Dr. Carl Gold, an evolutionary psychologist. Gold was in his mid-sixties, and with his trim build and gray mane of hair, would not be out of place in the boardroom of a major company or arguing on the floor of the senate. He was a leader in his field with a worldwide reputation.
Gold had invited three men he knew by reputation as giants in their own fields. He also knew them all personally, in varying degrees, and was confident that what was discussed this stormy night would not go beyond the walls of his study.
Across from Gold sat Fred Fielding. Tall and gaunt, Fielding had a permanent tan from his many field trips as physical anthropologist. Next to Fielding was John Sanders, a world-renowned human geneticist. Sanders published his work in all the major journals, but most of his work was now tied up in the debate over the use of human stem cells. Sanders, with his short thick build, was the opposite of Fielding. With his thick black hair and swarthy complexion, he was often mistaken for a maintenance man. The broken nose he earned during his collegiate boxing career added to the image.
The last of the three invited guests was Dr. Bill Mark, a fertility specialist and adjunct professor in Yale’s medical school. Tall, slim and blond, with his athletic build, he appeared to be in his mid-forties although he was well on the way to sixty. As each man introduced himself and discussed their specialties, Mark wondered if he had been summoned to this meeting by mistake. His discipline did not fit in with the others present. He was not a researcher. He was a physician.
Gold surveyed his colleagues and friends. “Gentlemen, the storm that rages beyond these walls will be dwarfed by the storm that may rage within these walls tonight. I’m sure you are all aware of the magnificent discovery made in the Swiss Alps. The body of a perfectly preserved Neanderthal, using carbon dating, is estimated to be thirty thousand years old. I have spent my life studying these creatures. From the time the first Neanderthal skull was found in 1848, this subset of man has remained a mystery. We are still trying to fathom the extent of their intelligence and how they fit into the human tree of development.
“There are many facts about these distant relatives of modern man that lead to fascinating conjecture. To begin with, their brains were ten percent larger than that of modern man, yet they are thought to be simple brutes. We now know that Neanderthals manufactured tools and produced art. The mask found on the banks of the Loire in France was an unexpected find. The fact that they produced art indicates they had an appreciation of life beyond their own existence. They apparently did lack one skill. They were not as adept at fashioning weapons as their fellow bipeds.
“Another intriguing discovery found in the Kabara Cave in Israel was a Neanderthal bone of extreme importance. The bone I refer to was a Neanderthal hyoid bone. This find dispels the theory that Neanderthals could do nothing but grunt. The presence of a hyoid bone indicates they were capable of speech. Taking into consideration other aspects of their skulls, it is thought that Neanderthals had a high, nasal voice.
“There are many questions to be answered, and now we have the means at our disposal to journey from conjecture to fact. I have obtained a sample of the newly discovered Neanderthal. The reason I have called you all together this evening is to formulate a plan, that my utilizing modern genetics and in vitro fertilization will produce a Neanderthal. We shall be able to answer all the questions that have plagued modern man about the Neanderthal enigma.”
Fred Fielding was the first to speak. “As a physical anthropologist, I look forward to examining the body of the recently discovered Neanderthal. But your point is clear. To see how the physical characteristics, whose meaning we assume to deduce, come into play in a living specimen would mean phenomenal advances in our knowledge of man’s distant relative.”
John Sanders, the geneticist, now spoke up. “With a specimen from this newly discovered Neanderthal, modern genetics could solve, once and for all, the debate of where Neanderthals reside in man’s family tree. However, what you propose is to produce a living individual. To do that would require cloning, a method too dangerous to try on a human – to say nothing about it being illegal.”
Gold said, “My dear Dr. Sanders, you would not be cloning a member of the Homo sapiens species. You would be cloning an example of Homo neanderhtalensis.”
A smile crept across Sanders’ face. This argument would be viable, until the law caught up with the science. “In that case, I am willing to isolate the DNA. What we would need next is a human egg and female willing to carry the Neanderthal to term.”
All eyes were now on Dr. Mark, the fertilization specialist. He said, “I now see where I fit in. I see how we all fit into this project. I will not mince words. I feel uncomfortable about this proposition. The mechanisms of the plan would be simple. I have a supply of donor eggs. We can remove the egg’s DNA and use cloning methods described in the literature, insert Neanderthal DNA and initiate mitosis. I also have a group of women we use in my practice who are willing to carry babies as surrogate mothers but refuse to see the baby after birth. They want no chance to form an attachment to the child.
“I think the experiment Dr. Gold proposes can be accomplished. My question is should it be done? By using the scientific name of the Neanderthal as a loophole, we feel we are free to create an individual who may possess human emotions, who may possess a soul. This is much different than cloning a sheep or a cat, no matter how much we choose to belittle the difference. I am not sure I can proceed with this endeavor.”
Gold said, “I picked you, Bill, because I knew you would not go easily with this plan. What we are planning to do is of profound importance, and also of profound scientific and moral complexity. Yet, for science to advance, sometimes risks must be taken. I appreciate your arguments. I know there are risks, but we have the capacity to venture into the unknown and bring light to a land of mystery. Through our expertise we can gain knowledge of the beginning of our humanity.”
The debate went on until dawn lit the study windows. Fielding and Sanders warmed up to their initial confidence. Mark persisted in his initial skepticism. But in the end, as a new day on Earth began, a new chapter in mankind’s knowledge was agreed upon.
THE CLONING
John Sanders received frozen tissue samples from Gold. As he gazed at the sample packed in dry ice, he could not believe he was peering into a box containing a tissue sample of a ‘man’ dead thirty thousand years. Sanders’ ego did not get the better of him. He knew he had been out of the lab for too long to attempt the important work that lay ahead. He employed a promising PhD candidate, Michael Rose, to do the actual work. He would tell Rose as little as possible about the nature of the experiment. The meeting at Gold’s study had left him with the feeling that he was involved in a conspiracy rather than an experiment, the fewer people that knew about the true purpose of the experiment, the better.
Sanders’ first meeting with Rose went well. “Michael, I would like you to help me in a special project.”
“Certainly Dr. Sanders. I’m a little desperate for a new project now that the study I’m working on is going nowhere.”
Sanders said, “It’s a cloning experiment.”
“Fantastic,” said Rose. “What will we be cloning?”
Sanders hesitated, and then answered, “A non-human primate.”
“Has that ever been done before Dr. Sanders?”
“Not to my knowledge. We would be making history.”
Rose could not believe his luck. He was going from a dead-end research project to an historic experiment.
“When do we begin?”
“Immediately,” Sanders said. “I already have a tissue sample from which you can extract the DNA for the cloning. I also have a list of references I want you to read and extract from them the method used to fertilize the egg and develop it into an embryo.”
* * *
Two weeks later Rose had the DNA extracted and the materials he would need for the union of the egg and extracted DNA to begin their journey to a living entity.
Sanders called Mark, “Bill, we’re ready to implant the DNA into the eggs.”
“I’ll ship them out by express mail,” said Mark. “Good luck!”
The eggs arrived in a container of liquid nitrogen. The paperwork indicated that there were ten eggs contained in the container. When all was ready, with Sanders at his side, Rose began the cloning experiment.
The eggs were rapidly thawed. Once thawed, Rose removed their DNA and inserted the ‘primate DNA’ he had prepared. Each egg was given its own petri dish of life sustaining fluids and put into an incubator.
Both Sanders and Rose periodically checked on the eggs. Initially, all ten began to divide. But soon four of the small balls of cells died. The remaining six progressed to a point where they could be slowly cooled, then frozen and stored in liquid nitrogen until they could be implanted into a uterus.
Rose was excited as he entered Sanders’ office. “Dr. Sanders, the embryos are frozen. I’m looking forward to seeing the results of the experiment.”
Sanders said, “I’ll let you know how things progress.”
“Do we have the monkeys that will carry the embryos to term here?”
“No Michael, the implantation will be done at another institution.”
After Rose left, Sanders sat at his desk and thought, You’ll be told the embryos all died after implantation. For you, this experiment is over.
Strangely, Sanders found himself feeling envy for Rose. His dreams had recently been haunted by what this adventure might produce.
TO BE CONTINUED
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